产品中心
一、蛋白类肿瘤标记物检测试剂盒
1. 产品序号：KA0001
（1）. 产品名称（检测试剂盒）：A1AT（alpha-1-antitrypsin precursor）
（2）. 蛋白质ID：NP_000286.3
（3）. 基因ID：NM_000295.5
（4）. 检测方法类型：Elisa
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.
（9）. 参考文献：Verathamjamras, Chris et al. “Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer.” Clinical proteomics vol. 20,1 15. 6 Apr. 2023, doi:10.1186/s12014-023-09407-y.
Xie, Li-Qi et al. “Novel proteomic strategy reveal combined alpha1 antitrypsin and cathepsin D as biomarkers for colorectal cancer early screening.”Journal of
proteome research vol. 9,9 (2010): 4701-9. doi:10.1021/pr100406z.
2. 产品序号：KA0002
（1）. 产品名称（检测试剂盒）：ADAM10（disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein）
（2）. 蛋白质ID：NP_001101.1
（3）. 基因ID：NM_001110.4
（4）. 检测方法类型：Elisa
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：Members of the ADAM family are cell surface proteins witha unique structure possessing both potential adhesi on and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.
（9）. 参考文献：Dash, Srinivas et al. “Extracellular Vesicle Membrane Protein Profiling and Targeted Mass Spectrometry Unveil CD59 and Tetraspanin 9 as Novel Plasma Biomarkers for Detection of Colorectal Cancer.” Cancers vol. 15,1 177. 28 Dec. 2022, doi:10.3390/cancers15010177.
3. 产品序号：KA0003
（1）. 产品名称（检测试剂盒）：A2M （alpha-2-macroglobulin）
（2）. 蛋白质ID：NP_000005.3
（3）. 基因ID：NM_000014.6
（4）. 检测方法类型：Elisa
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：The protein encoded by this gene is a protease inhibitor and cytokine transporter.It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
（9）. 参考文献：Zhang, Guanran et al. “A2M is a potential core gene in intrahepatic cholangiocarcinoma.” BMC cancer vol. 22,1 5. 3 Jan. 2022, doi:10.1186/s12885-021-09070-2.
Ma, Qiang et al. “Identification and validation of key genes associated with non-small-cell lung cancer.” Journal of cellular physiology vol. 234,12 (2019): 22742-22752. doi:10.1002/jcp.28839
4. 产品序号：KA0004
（1）. 产品名称（检测试剂盒）：AFP（alpha fetoprotein）
（2）. 蛋白质ID：NP_001125.1
（3）. 基因ID：NM_001134.3
（4）. 检测方法类型：Elisa
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer.The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
（9）. 参考文献：Force M, Park G, Chalikonda D, Roth C, Cohen M, Halegoua-DeMarzio D, Hann HW. Alpha-Fetoprotein (AFP) and AFP-L3 Is Most Useful in Detection of Recurrence of Hepatocellular Carcinoma in Patients after Tumor Ablation and with Low AFP Level. Viruses. 2022 Apr 8;14(4):775. doi: 10.3390/v14040775. PMID: 35458505; PMCID: PMC9031551.
5. 产品序号：KA0005
（1）. 产品名称（检测试剂盒）：AFP-L1，L2，L3
（2）. 蛋白质ID：
（3）. 基因ID：
（4）. 检测方法类型：Liquid-phase binding assay
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：Based on its binding capability to lectin Lens Culinaris Agglutinin (LCA), and total AFP can be separated into three different glycoforms, AFP-L1, AFP-L2, and AFP-L3.
（9）.参考文献：Hann H.W., Li D., Yamada H., Satomura S., Coben R., DiMarino A. Helpfulness of highly sensitive AFP-L3 and DCP in surveillance for hepatocellular carcinoma in patient with a normal alpha-fetoprotein. J. Med. Microb. Diagn. 2014;3:130.
6. 产品序号：KA0006
（1）. 产品名称（检测试剂盒）：AFU (Alpha-1 fucosidase)
（2）. 蛋白质ID： NP_000138.2
（3）. 基因ID： NM_000147.5
（4）. 检测方法类型：酶化学法
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：单管
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description)：The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis(FUCA1D), which is an autosomalrecessive lysosomal storage disease.
（9）. 参考文献：Prabhu, Sunaina Kiran et al. “Comparative studies on the substrate specificity and defucosylation activity of three α-l-fucosidases using synthetic fucosylated glycopeptides and glycoproteins as substrates.” Bioorganic & medicinal chemistry vol. 42 (2021): 116243. doi:10.1016/j.bmc.2021.116243
7. 产品序号：KA0007
（1）. 产品名称（检测试剂盒）：AFP-L1，L2，L3
（2）. 蛋白质ID： NP_000138.2
（3）. 基因ID： NM_000147.5
（4）. 检测方法类型：Elisa
（5）. 应用：（人）血清含量浓度测定 (ng/ml)
（6）. 规格：96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：
（9）. 参考文献：Zhang, Meng et al. “Serum α-l-fucosidase activities are significantly increased in patients with preeclampsia.” Progress in molecular biology and translational science vol. 162 (2019): 349-362. doi:10.1016/bs.pmbts.2018.12.008
Liang, En-Yu et al. “Clinical relevance of serum α-l-fucosidase activity in the SARS-CoV-2 infection.” Clinica chimica acta; international journal of clinical chemistry vol. 519 (2021): 26-31. doi:10.1016/j.cca.2021.03.031
8. 产品序号：KA0008
（1）. 产品名称（检测试剂盒）：AGP1，ANGP1（angiopoietin 1）
（2）. 蛋白质ID： NP_001137.2
（3）. 基因ID： NM_001146.5
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）： A secreted glycoprotein that belongs to the angiopoietin family playing important roles in vascular development and angiogenesis.Mutations in this gene are associated with hereditary angioedema.
（9）. 参考文献：Zalewska-Ziob, Marzena et al. “Prognostic value of tumour tissue ANG-1 expression and Ang-1 concentration in patients with non-small-cell lung cancer.” Polish journal of pathology : official journal of the Polish Society of Pathologists vol. 73,1 (2022): 6-13. doi:10.5114/pjp.2022.117176.
Tsai, Teresa et al. “Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy.” PloS one vol. 18,1 e0280488. 20 Jan. 2023, doi:10.1371/journal.pone.0280488
9. 产品序号：KA0009
（1）. 产品名称（检测试剂盒）：AZGP1（alpha-2-glycoprotein 1, zinc-binding）
（2）. 蛋白质ID： NP_001176.1
（3）. 基因ID： NM_001185.4
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：nvolved in cell adhesion and detection of chemical stimulus involved in sensory perception of bitter taste. Located in extracellular space.
（9）. 参考文献：Chan, Gordon Chun-Kau et al. “Adipose and serum zinc alpha-2-glycoprotein (ZAG) expressions predict longitudinal change of adiposity, wasting and predict survival in dialysis patients.” Scientific reports vol. 12,1 9087. 31 May. 2022, doi:10.1038/s41598-022-13149-6.
Huscher, Dörte et al. “Development of a prediction model for mortality and cardiovascular outcomes in older adults taking into account AZGP1.” Scientific reports vol. 11,1 11792. 3 Jun. 2021, doi:10.1038/s41598-021-91169-4
10. 产品序号：KB00010
（1）. 产品名称（检测试剂盒）： BCAT1（branched chain amino acid transaminase 1）
（2）. 蛋白质ID： NP_001171562.1
（3）. 基因ID： NM_001178091.2
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）： This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia.
（9）. 参考文献：Ding, Yifeng et al. “BCAT1, as a prognostic factor for HCC, can promote the development of liver cancer through activation of the AKT signaling pathway and EMT.” Journal of molecular histology vol. 54,1 (2023): 25-39. doi:10.1007/s10735-022-10108-3.
Li, Guo-Sheng et al. “BCAT1: A risk factor in multiple cancers based on a pan-cancer analysis.” Cancer medicine vol. 11,5 (2022): 1396-1412. doi:10.1002/cam4.4525
11. 产品序号：KB00011
（1）. 产品名称（检测试剂盒）： C3（complement C3）
（2）. 蛋白质ID： NP_000055.2
（3）. 基因ID： NM_000064.4
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）：Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity.
（9）. 参考文献：Saito, Satoshi et al. “Complement 3 Is a Potential Biomarker for Cerebral Amyloid Angiopathy.” Journal of Alzheimer's disease : JAD vol. 89,1 (2022): 381-387. doi:10.3233/JAD-220494
Pan, Xiao-Yu, and Zai-Wei Zhang. “MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy.” Cardiovascular therapeutics vol. 2020 1615826. 24 Jun. 2020, doi:10.1155/2020/1615826
12. 产品序号：KB00012
（1）. 产品名称（检测试剂盒）： C9（complement C9）
（2）. 蛋白质ID： NP_001728.1
（3）. 基因ID： NM_001737.5
（4）. 检测方法类型：Elisa/hybrid lectin
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）： This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
（9）. 参考文献：Narayanasamy, Arul et al. “Fucosylated glycoproteomic approach to identify a complement component 9 associated with squamous cell lung cancer (SQLC).” Journal of proteomics vol. 74,12 (2011): 2948-58. doi:10.1016/j.jprot.2011.07.019.
Shah, Alok K et al. “Serum Glycoprotein Biomarker Discovery and Qualification Pipeline Reveals Novel Diagnostic Biomarker Candidates for Esophageal Adenocarcinoma.” Molecular & cellular proteomics : MCP vol. 14,11 (2015): 3023-39. doi:10.1074/mcp.M115.050922
13. 产品序号：KB00013
（1）. 产品名称（检测试剂盒）：CA19-9
（2）. 蛋白质ID：
（3）. 基因ID：
（4）. 检测方法类型：Elisa/hybrid lectin
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
（8）. 描述（Target Description ）： Sialylated Lewis(a) blood group carbohydrate antigen found in many adenocarcinomas of the digestive tract, especially pancreatic tumors.5-Acetylneuraminyl-2-3-Galactosyl-1-3-(Fucopyranosyl-1-4)-N-Acetylglucosamine。Sialyl Lewis(a) Tetrasaccharide. alpha-Neu5Ac-(2-3)-beta-D-Gal-(1-3)-(alpha-L-Fuc-(1-4))-beta-D-GlcNAc。NAG-1,3-F-1,4-GN。Neu5Ac-2-3-Gal-1-3-(Fuc-1-4)-GlcNAc。Sialyl Lewis(a) Tetrasaccharide （9）. 参考文献：Ushida, Yuta et al. “High CA19-9 level in resectable pancreatic cancer is a potential indication of neoadjuvant treatment.” Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] vol. 21,1 (2021): 130-137. doi:10.1016/j.pan.2020.11.026.
Baghbanian, Mahmud et al. “Serum CA19-9 in patients with solid pancreatic mass.” Gastroenterology and hepatology from bed to bench vol. 6,1 (2013): 32-5.
14. 产品序号：KB00014
（1）. 产品名称（检测试剂盒）： CA15-3（mucin 1, cell surface associated）
（2）. 蛋白质ID： NP_001018016.1
（3）. 基因ID： NM_001018016.3
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com
( 8）. 描述（Target Description ）： This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. （9）. 参考文献：Duffy, Michael J et al. “CA 15-3: uses and limitation as a biomarker for breast cancer.” Clinica chimica acta; international journal of clinical chemistry vol. 411,23-24 (2010): 1869-74. doi:10.1016/j.cca.2010.08.039 Abdelwhab, Amira et al. “Expression of Mucin1 in saliva in oral squamous cell carcinoma and oral potentially malignant disorders (case control study).” Oral diseases vol. 29,4 (2023): 1487-1494. doi:10.1111/odi.14138
15. 产品序号：KB00015
（1）. 产品名称（检测试剂盒）： CA 72-4
（2）. 蛋白质ID： MeSH C083825
（3）. 基因ID： carbohydrate antigen 72-4
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）： CA 72-4 was EN to ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE 1992-94 （9）. 参考文献：Granato, Teresa et al. “Role of HE4, CA72.4, and CA125 in monitoring ovarian cancer.” Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine vol. 33,5 (2012): 1335-9. doi:10.1007/s13277-012-0381-8
Liu, Peng et al. “Elevated serum CA72-4 levels predict poor prognosis in pancreatic adenocarcinoma after intensity-modulated radiation therapy.” Oncotarget vol. 6,11 (2015): 9592-9. doi:10.18632/oncotarget.3562
16. 产品序号：KB00016
（1）. 产品名称（检测试剂盒）： CA-125（MUCIN16)
（2）. 蛋白质ID： NP_001401615.1
（3）. 基因ID： NM_001414686.1
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔
（7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）： Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. （9）. 参考文献：Plana, Alba et al. “Radiologically enlarged cardiophrenic lymph nodes and CA-125 in relation to diaphragmatic carcinomatosis, surgical outcome, and overall survival in advanced ovarian cancer.” Acta oncologica (Stockholm, Sweden) vol. 62,5 (2023): 451-457. doi:10.1080/0284186X.2023.2204993
Chan, John K et al. “The clinical and prognostic significance of pre-chemotherapy serum CA-125 in high-risk early stage ovarian cancer: An NRG/GOG ancillary study.” Gynecologic oncology vol. 167,3 (2022): 429-435. doi:10.1016/j.ygyno.2022.09.028
17. 产品序号：KB00017
（1）. 产品名称（检测试剂盒）： CA 242（Carbohydrate antigen 242 ）
（2）. 蛋白质ID： MeSH Unique ID: C074601
（3）. 基因ID： C074601
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）： CA 242 antigen，a new serum tumor marker in pancreatic carcinoma； Antigens, Tumor-Associated, Carbohydrate （9）. 参考文献：Hou, Shenghuai et al. “Evaluation of Clinical Diagnostic and Prognostic Value of Preoperative Serum Carcinoembryonic Antigen, CA19-9, and CA24-2 for Colorectal Cancer.” Alternative therapies in health and medicine, AT7969. 9 Jun. 2023
Rao, Hui et al. “Clinical Value of Serum CEA, CA24-2 and CA19-9 in Patients with Colorectal Cancer.” Clinical laboratory vol. 67,4 (2021): 10.7754/Clin.Lab.2020.200828. doi:10.7754/Clin.Lab.2020.200828
18. 产品序号：KB00018
（1）. 产品名称（检测试剂盒）： CAT（Catalase)
（2）. 蛋白质ID： NM_001752.4
（3）. 基因ID： NP_001743.1
（4）. 检测方法类型：Elisa/Enzyme
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）： a key antioxidant enzyme in the bodies defense against oxidative stress. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers.
（9）. 参考文献：PEIZER, L R, and D WIDELOCK. “A colorimetric test for measuring catalase activity of cultures of M. tuberculosis.” American review of tuberculosis vol. 71,2 (1955): 305-7. doi:10.1164/artpd.1955.71.2.305
Zhang, Hao et al. “Construction of a fecal immune-related protein-based biomarker panel for colorectal cancer diagnosis: a multicenter study.” Frontiers in immunology vol. 14 1126217. 29 May. 2023, doi:10.3389/fimmu.2023.1126217
19. 产品序号：KB00019
（1）. 产品名称（检测试剂盒）： CD59（CD59 glycoprotein preproprotein）
（2）. 蛋白质ID： NM_000611.6
（3）. 基因ID： NP_000602.1
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）： a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. （9）. 参考文献：Andrews, Chloe et al. “Plasma-glycated CD59 as an early biomarker for gestational diabetes mellitus: prospective cohort study protocol.” BMJ open vol. 12,4 e054773. 20 Apr. 2022, doi:10.1136/bmjopen-2021-054773
Dash, Srinivas et al. “Extracellular Vesicle Membrane Protein Profiling and Targeted Mass Spectrometry Unveil CD59 and Tetraspanin 9 as Novel Plasma Biomarkers for Detection of Colorectal Cancer.” Cancers vol. 15,1 177. 28 Dec. 2022, doi:10.3390/cancers15010177
20. 产品序号：KB00020
（1）. 产品名称（检测试剂盒）： CDH17（cadherin 17）
（2）. 蛋白质ID： NM_001144663.2
（3）. 基因ID： NP_001138135.1
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. （9）. 参考文献：Zheng, Bo-Hao et al. “Clinical correlation of cadherin-17 marker with advanced tumor stages and poor prognosis of cholangiocarcinoma.” Journal of surgical oncology vol. 123,5 (2021): 1253-1262. doi:10.1002/jso.26399
Lopes, Nair et al. “A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis.” Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association vol. 23,5 (2020): 811-823. doi:10.1007/s10120-020-01064-6
21. 产品序号：KB00021
（1）. 产品名称（检测试剂盒）： CDHR5（cadherin 5）
（2）. 蛋白质ID： NM_001795.5
（3）. 基因ID： NP_001786.2
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description )：a classical cadherin of the cadherin superfamily. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance.
（9）. 参考文献：Xu, Lei et al. “Pan-Cancer Analysis Identifies CHD5 as a Potential Biomarker for Glioma.” International journal of molecular sciences vol. 23,15 8489. 30 Jul. 2022, doi:10.3390/ijms23158489
Zhou, Yong et al. “Expression of CHD5 may serve as an independent biomarker of prognosis in colorectal cancer via immunohistochemical staining.” International journal of clinical and experimental pathology vol. 11,5 2792-2798. 1 May. 2018
22. 产品序号：KB00022
（1）. 产品名称（检测试剂盒）： CEA（CEA cell adhesion molecule 5） （2）. 蛋白质ID： NM_001291484.3
（3）. 基因ID： NP_001278413.1
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. （9）. 参考文献：Kim, Hyeong Seok et al. “Serum carcinoembryonic antigen and carbohydrate antigen 19-9 as preoperative diagnostic biomarkers of extrahepatic bile duct cancer.” BJS open vol. 5,6 (2021): zrab127. doi:10.1093/bjsopen/zrab127
Süer, Hande et al. “Combination of CEACAM5, EpCAM and CK19 gene expressions in mediastinal lymph node micrometastasis is a prognostic factor for non-small cell lung cancer.” Journal of cardiothoracic surgery vol. 18,1 189. 13 Jun. 2023, doi:10.1186/s13019-023-02297-z
23. 产品序号：KB00023
（1）. 产品名称（检测试剂盒）： CEACAM8（CEA cell adhesion molecule 8） （2）. 蛋白质ID： NM_001816.4
（3）. 基因ID： NP_001807.2
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：Enables protein heterodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cell surface and extracellular space. Biomarker of severe acute respiratory syndrome.
（9）. 参考文献： Kovaleva, O V et al. “Clinical Significance of CD66b Expression in Non-Small Cell Lung Cancer.” Bulletin of experimental biology and medicine vol. 174,6 (2023): 779-783. doi:10.1007/s10517-023-05797-z
Skov, Vibe et al. “A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis.” PloS one vol. 11,8 e0161570. 31 Aug. 2016, doi:10.1371/journal.pone.0161570
24. 产品序号：KB00024
（1）. 产品名称（检测试剂盒）： CK7（keratin 7）
（2）. 蛋白质ID： NM_005556.4
（3）. 基因ID： NP_005547.3
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ） ：The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.
（9）. 参考文献： Song, Jianlu et al. “Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.” BMC cancer vol. 22,1 894. 16 Aug. 2022, doi:10.1186/s12885-022-09983-6
Woods, Robbie S R et al. “Cytokeratin 7 and 19 expression in oropharyngeal and oral squamous cell carcinoma.” European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery vol. 279,3 (2022): 1435-1443. doi:10.1007/s00405-021-06894-3
25. 产品序号：KB00025
（1）. 产品名称（检测试剂盒）： CK15 (keratin 15）
（2）. 蛋白质ID： NM_002275.4
（3）. 基因ID： NP_002266.3
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins.
（9）. 参考文献： Rao, X et al. “KRT15 overexpression predicts poor prognosis in colorectal cancer.” Neoplasma vol. 67,2 (2020): 410-414. doi:10.4149/neo_2019_190531N475
Lin, Jian-Bo et al. “KRT 15 as a prognostic biomarker is highly expressed in esophageal carcinoma.” Future oncology (London, England) vol. 16,25 (2020): 1903-1909. doi:10.2217/fon-2019-0603
26. 产品序号：KB00026
（1）. 产品名称（检测试剂盒）： CK18（keratin 18）
（2）. 蛋白质ID： NM_000224.3
（3）. 基因ID： NP_000215.1
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.
（9）. 参考文献： Eguchi, Akiko et al. “A new detection system for serum fragmented cytokeratin 18 as a biomarker reflecting histologic activities of human nonalcoholic steatohepatitis.” Hepatology communications vol. 6,8 (2022): 1987-1999. doi:10.1002/hep4.1971
Singh Bhangu, Jagdeep et al. “Circulating caspase-cleaved cytokeratin 18 correlates with tumour burden and response to therapy in patients with colorectal cancer liver metastasis.” Clinica chimica acta; international journal of clinical chemistry vol. 538 (2023): 53-59. doi:10.1016/j.cca.2022.11.009
27. 产品序号：KB00027
（1）. 产品名称（检测试剂盒）： CK20（keratin 20）
（2）. 蛋白质ID： NM_019010.3
（3）. 基因ID： NP_061883.1
（4）. 检测方法类型：IHC/Elisa
（5）. 应用： FFPE/(人)血浆浓度测定(ng/ml)
（6）. 规格： 96 slides/孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa.
（9）. 参考文献：Sakata, Yasuhiro et al. “The clinical significance of cytokeratin 20 staining pattern in Merkel cell carcinoma.” Drug discoveries & therapeutics vol. 15,3 (2021): 162-165. doi:10.5582/ddt.2021.01043
Shan, Ke-Shu et al. “Usefulness of large-section cytokeratin 20 in the detection of intestinal wall infiltration and mesangial metastasis in patients with middle and lower rectal cancer.” Journal of cancer research and therapeutics vol. 15,2 (2019): 437-441. doi:10.4103/jcrt.JCRT_405_18
28. 产品序号：KB00028
（1）. 产品名称（检测试剂盒）： CP（ceruloplasmin，CP2）
（2）. 蛋白质ID： NM_000096.4
（3）. 基因ID： NP_000087.2
（4）. 检测方法类型： Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96 孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin.
（9）. 参考文献： Mukae, Yuta et al. “Ceruloplasmin Levels in Cancer Tissues and Urine Are Significant Biomarkers of Pathological Features and Outcome in Bladder Cancer.” Anticancer research vol. 41,8 (2021): 3815-3823. doi:10.21873/anticanres.15174
Lazar-Poloczek, Elżbieta et al. “Ceruloplasmin as Redox Marker Related to Heart Failure Severity.” International journal of molecular sciences vol. 22,18 10074. 17 Sep. 2021, doi:10.3390/ijms221810074
29. 产品序号：KB00029
（1）. 产品名称（检测试剂盒）： CTHRC1(collagen triple helix repeat containing 1) （2）. 蛋白质ID： NM_001256099.2
（3）. 基因ID： NP_001243028.1
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96 孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ） ： a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. （9）. 参考文献： Baiken, Yeldar et al. “Elevated Levels of Plasma Collagen Triple Helix Repeat Containing 1 (CTHRC1) Are Strongly Associated with eGFR and Albuminuria in Chronic Kidney Disease.” Medicina (Kaunas, Lithuania) vol. 59,4 651. 24 Mar. 2023, doi:10.3390/medicina59040651
Meng, Chuang et al. “CTHRC1 is a prognosis-related biomarker correlated with immune infiltrates in colon adenocarcinoma.” World journal of surgical oncology vol. 20,1 89. 20 Mar. 2022, doi:10.1186/s12957-022-02557-7
30. 产品序号：KB00030
（1）. 产品名称（检测试剂盒）： CYFRA 21-1(antigen CYFRA21.1) （2）. MeSH Unique ID: C102012 （3）. 检测方法类型：Elisa
（4）. 应用： (人)血清含量浓度测定(ng/ml)
（5）. 规格： 96 孔 （6）. 咨询：kenmore@163.com （7）. 描述（Target Description ）：a cytokeratin related marker, serum concentrations of which show promising diagnostic utility in patients with bladder cancer
（8）. 参考文献： Spagnolo, Paolo, and Justin M Oldham. “On Target: CYFRA 21-1 as an Idiopathic Pulmonary Fibrosis Biomarker.” American journal of respiratory and critical care medicine vol. 205,12 (2022): 1376-1377. doi:10.1164/rccm.202203-0474ED
Hyun, Jae-Won et al. “CYFRA 21-1 levels in cerebrospinal fluid as a putative therapeutic monitoring biomarker for patients with leptomeningeal carcinomatosis: A pilot study.” Cancer biomarkers : section A of Disease markers vol. 28,1 (2020): 81-89. doi:10.3233/CBM-190187
31. 产品序号：KB00031
（1）. 产品名称（检测试剂盒）： hsCRP(C-reactive protein) （2）. 蛋白质ID： NM_000567.3
（3）. 基因ID： NP_000558.2
（4）. 检测方法类型：Elisa
（5）. 应用： (人)血清含量浓度测定(ng/ml)
（6）. 规格： 96 孔 （7）. 咨询：kenmore@163.com （8）. 描述（Target Description ）：The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators.
（9）. 参考文献： Abdullateef Abdullah, Z, and L Fouad Ali. “Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity.” Archives of Razi Institute vol. 78,2 737-742. 30 Apr. 2023, doi:10.22092/ARI.2022.359731.2466
Deme, Dániel, and András Telekes. “A C-reaktív protein (CRP) plazmaszintjének prognosztikai jelentősége az onkológiában” [Prognostic importance of plasma C-reactive protein (CRP) in oncology]. Orvosi hetilap vol. 158,7 (2017): 243-256. doi:10.1556/650.2017.30646
